Eur J Pediatr (2000) 159: 299-301

Does growth hormone therapy improve motor development in infants with Prader-Willi syndrome?
Urs Eiholzer · Sigrun Malich · Dagmar I'Allemand

In infants with Prader-Willi syndrome (PWS), only milestones of development have been retrospectively assessed so far [2, 7]. In our study on growth hormone (GH) treatment in young children with PWS, we found a typical pattern of psychomotor retardation with these children being more retarded on the 'locomotor' and the 'hearing and speech' scale than on the other scales. Under GH treatment, motor development improved significantly, while speech development did not.